Abstract Background C3 glomerulopathy (C3G) is a rare, but severe glomerular disease with grim prognosis.The complex pathogenesis is just unfolding, and involves acquired as well as inherited dysregulation of the filter wire alternative pathway of the complement cascade.Currently, there is no established therapy.Treatment with the C5 complement inh
Differential phylogenetic expansions in BAHD acyltransferases across five angiosperm taxa and evidence of divergent expression among Populus paralogues
Abstract Background BAHD acyltransferases are involved in the synthesis and elaboration of a wide variety of secondary metabolites.Previous research has shown that characterized proteins from this family fall broadly into five major clades and contain two conserved protein motifs.Here, we aimed to expand the understanding of BAHD acyltransferase di
Mechanical safety of eccentrically compressed RC-column in the event of emergency impact
The safety analysis of the outermost column of the 8 m high building stylobate was performed under eccentric compression.The bending moments act in two main planes.Modeling DRY of the emergency based on physical and geometrical nonlinear calculation in dynamic statement is proposed.The dynamic overload is modeled simultaneously by longitudinal forc
Modelling surface subsidence of coal mines using a bonded block numerical method
Surface subsidence is common geologic hazard in coal mines when longwall mining method is applied.In this research, a Bonded Block Model (BBM) is selected to numerically simulate and analyze the surface subsidence of coal mines.Parametric study is conducted and key factors controlling the subsidence are characterized.BBM filter wire models with no
Predicting falls in older adults: an umbrella review of instruments assessing gait, balance, and functional mobility
Abstract Background To Dryer Humidity Sensor Plug review the validated instruments that assess gait, balance, and functional mobility to predict falls in older adults across different settings.Methods Umbrella review of narrative- and systematic reviews with or without meta-analyses of all study types.Reviews that focused on older adults in any set