Treating C3 glomerulopathy with eculizumab

Abstract Background C3 glomerulopathy (C3G) is a rare, but severe glomerular disease with grim prognosis.The complex pathogenesis is just unfolding, and involves acquired as well as inherited dysregulation of the filter wire alternative pathway of the complement cascade.Currently, there is no established therapy.Treatment with the C5 complement inh

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Differential phylogenetic expansions in BAHD acyltransferases across five angiosperm taxa and evidence of divergent expression among Populus paralogues

Abstract Background BAHD acyltransferases are involved in the synthesis and elaboration of a wide variety of secondary metabolites.Previous research has shown that characterized proteins from this family fall broadly into five major clades and contain two conserved protein motifs.Here, we aimed to expand the understanding of BAHD acyltransferase di

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Predicting falls in older adults: an umbrella review of instruments assessing gait, balance, and functional mobility

Abstract Background To Dryer Humidity Sensor Plug review the validated instruments that assess gait, balance, and functional mobility to predict falls in older adults across different settings.Methods Umbrella review of narrative- and systematic reviews with or without meta-analyses of all study types.Reviews that focused on older adults in any set

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